Understanding the genetic sequence of individual patients is becoming an important feature of medical care. This is particularly true in cancer, where the accumulation of genetic alterations in the tumor represents a universal feature of the disease and can be important for determining optimal therapy and for disease monitoring. Personal Genome Diagnostics (PGDx) was launched in 2010 to bring state-of-the-art genetic analyses to cancer researchers, physicians and patients. The founders of PGDx are international leaders in cancer genetics and were the first to perform genome-wide sequence analyses of human cancer. PGDx has developed proprietary methods to perform patient-specific analyses of the cancer genome using advanced tools and technologies.